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2-Butynediamide

2-Butynediamide

  • Cellocidin
  • Lenamycin
  • Acetylene diamide
  • Acetylenedicarboxamide
  • Acetylenedicarboxylic acid diamide
FormulaC4H4N2O2 (C4H4N2O2)
Description Solid.

Registry Numbers and Inventories.
CAS543-21-5
RTECSAO9900000
RTECS class Drug (D); Mutagen (M); Natural Product (N)
Merck12,2009
Beilstein ref.4-02-00-02295
Listed on the Toxic Substancs Control Act (TSCA).
Listed on Canadian Non-Domestic Substances List (NDSL).

Properties.
Formula mass112.08
Melting point, °C179
Solubility in waterVery soluble
Acid/Base13.01 (pka)

Hazards and Protection.
Storage Store in a cool, dry place. Keep container closed when not in use.
Handling Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get on skin or in eyes. Do not ingest or inhale.
Protection Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability Stable under normal temperatures and pressures.
Incompatibilities Strong oxidizing agents.
Decomposition Irritating and toxic fumes and gases.

Fire.
Flash Point,°C216
Fire fighting Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Exposure effects
Ingestion
May be fatal if swallowed. Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation
Causes respiratory tract irritation.
Skin
Causes skin irritation. Harmful if absorbed through the skin.
First aid 
Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.


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